Chicken Artichoke Casserole is a simple and delicious way to bake chicken for dinner or meal prep for lunches—and sneak some tasty veggies onto your plate! Artichoke hearts and mushrooms add bold flavor while the cheese covers the chicken in all its creamy, melty goodness. Chicken Artichoke Casserole is ready in just 45 minutes and serves 4. Leftovers taste even better the next day!

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  • 1 cup Parmesan cheese, grated
  • 1 cup light mayonnaise
  • garlic powder, to taste
  • 4 (4-ounce) chicken breast halves, skinless, boneless
  • 1 (14-ounce) can artichoke hearts, drained
  • 2 cups fresh spinach
  • 1 (8-ounce) package crimini mushrooms, sliced


Step 1 –Preheat the oven to 350 degrees F.

Step 2 –In a mixing bowl, combine the Parmesan, mayo, and garlic powder.

Step 3 –Lay the chicken breasts in a 9×13-inch baking dish.

Step 4 –Top with the drained artichoke hearts and crimini mushrooms.

Step 5 –Sprinkle the spinach over the dish, and finish by spreading the cheese mixture over top.

Step 6 –Bake until the chicken is fully cooked and the juices run clear, about 30 minutes.

Step 7 –Serve and enjoy!