How Long After Vyvanse Can I Take Tramadol (And Why)?

How Long After Vyvanse Can I Take Tramadol (And Why)?

Exact Answer: After 4 – 6 hours

Tramadol and Vyvanse are two medicines with different chemical compositions. Tramadol is also known as tramazoline, this is used in the treatment as a pain killer after major operations. Similarly, Vyvanse is also known as lisdexamfetamine, this is used in the treatment of attention deficit hyperactive disorder and also in increasing the attention to stay stabilized or focused.

We can not take both the medicines that are Tramadol and Vyvanse at a time. So an interval is kept between taking the doses of both the medicine as prescribed by doctors. Both have their functions for the treatment of different diseases and to show their effects.

How Long After Vyvanse Can I Take Tramadol

How Long After Vyvanse Can I Take Tramadol?

For childAfter 4 hours
For adultsAfter 6 hours

One should carefully read the prescription given by the doctors and should collect the information about the medicines i.e. tramadol and Vyvanse. These medicines are taken by mouth according to the dosage prescribed by the doctor. Varieties of factors that decide the particular dosage, age, and health condition help to decide the dosages. According to its working doses may increase gradually. 

In case of taking both doses, one should be very careful of the time interval between them that is 4 – 6 hours. Initially, after consuming Vyvanse we have to wait for 4– 6 hours for consuming tramadol, otherwise, it may show some side effects or risky health issues. Hence, the several doses and the time interval is the most important thing to look after while taking both the medication in one day. Or else, we should ask someone to remind us about the important details in time.

Tramadol is an opioid. It is mainly prescribed as a pain medication for treating moderate to moderately severe pain. When consumed in oral mode, in the formulation of immediate-release tablets, the process of pain relief begins within an hour. The formula is also available by injection. This is used as a long-lasting formulation. This medicine is mostly used by doctors after operations.


Lisdexamfetamine is mainly used to treat ADHD in people beyond five years. It is sold under the name Vyvanse among others, is a medication that is a derivative of amphetamine. Lisdexamfetamine is taken orally by mouth. In the United Kingdom, methylphenidate is more preferred as a company to this. It starts showing effects within 2 hours which may last for up to 14 hours. 

Why Can I Take Tramadol So Long After Vyvanse?

Before discussing further, we all should be aware that we should not take Tramadol and Vyvanse together. Taking Tramadol and Vyvanse together can have adverse side effects like dizziness, fatigue, drowsiness, inability to concentrate, and lack of coordination. Combining tramadol and Vyvanse can be especially dangerous for the elderly. 

Drugs react when taken in combination with other medications. The effects of the required medication can be intensified. Sometimes, their combined side effects could cause a horrible and painful chain of physical reactions. The main reason why both the chemically strong medicine that is Tramadol and Vyvanse should not be consumed together is that there are chances of addiction and withdrawal. In case, a person gets accustomed to frequently taking both the medications together, it may lead to serious consequences. The person may require residential addiction treatment to quit the addiction. Some adverse side effects of tramadol include a feeling of dizziness, hallucinations, loss of memory and coordination, slurred speech, troubles in breathing.

These symptoms are noticed when Tramadol is taken in extreme doses.  Such people develop a tolerance limit towards it. They further take a higher dosage more to experience the same effects. As a result, this can quickly turn into dependency. Some possible side effects of Vyvanse include dryness in the mouth, feeling of dizziness, constipation, pain in the stomach and abdomen, blurred speech and vision, etc.


Because of its main ingredient, lisdexamfetamine, Vyvanse is addictive. As an over-the-counter medicine, many people have access to it in tablets, capsules, and liquid form.

So as both are such high addictive medicines, taking them at a time may lead to high dizziness or severe side effects in the body which may lead to cardiac arrest and high blood pressure or numbness or weakness in the body. This may also need the dependency of the human towards these drugs which will affect our body more and more.


As we know, excess of everything may lead to a highly destructive environment. Exactly, in the same way, excess drugs used may lead to serious risk towards one’s life. These types of medicines are taken when our body doesn’t improve in the less power-dosed medicine and stays in the risky condition.

Those medicines are not provided without a prescription in the medical stores because they can be dangerous or fatigue.


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25 thoughts on “How Long After Vyvanse Can I Take Tramadol (And Why)?”

  1. I find it concerning that both Tramadol and Vyvanse are highly addictive. The potential consequences of their combined use are alarming.

    1. Indeed, it’s important to prioritize one’s health and be cautious about medication interactions and side effects.

    2. The potency of these medications is indeed a cause for concern. We should heed the warnings about their combined use.

  2. The information provided about the time intervals between taking Tramadol and Vyvanse is very useful. I will ensure to follow these guidelines for my health safety.

  3. It’s clear that strict adherence to medical prescriptions and advice is essential when it comes to Tramadol and Vyvanse. One must prioritize health over convenience.

    1. Health should indeed be the top priority, and proper understanding of interactions between medications is crucial.

    2. Absolutely, the risks associated with the combined use of these medications emphasize the need for caution.

  4. The detailed information provided about the effects of Tramadol and Vyvanse is enlightening. Awareness about their proper usage is crucial.

    1. Avatar of Harrison Gordon
      Harrison Gordon

      The risks associated with these medications underscore the importance of informed decision-making regarding their consumption.

  5. Avatar of Duncan Marshall
    Duncan Marshall

    The potential consequences of misusing Tramadol and Vyvanse are concerning. Heightened awareness and prudence are essential when dealing with these medications.

    1. Absolutely, the information highlights the importance of responsible consumption and understanding the potential risks involved with these medications.

  6. I had no idea that taking Tramadol and Vyvanse together could have such dangerous side effects. Thank you for sharing this valuable information.

    1. Yes, it’s crucial to be aware of these risks. High doses of both medications can lead to addiction and serious health issues.

  7. The detailed explanation of Tramadol and Vyvanse effects and interactions is insightful. It underscores the importance of responsible medication usage.

    1. Absolutely, the gravity of their combined effects necessitates careful monitoring and adherence to professional medical guidance.

    2. The potential harm from the concurrent use of these medications emphasizes the crucial role of informed and cautious consumption.

  8. The information about the dangers of combining Tramadol and Vyvanse is concerning and necessitates careful attention to medical advice.

    1. Indeed, the potential harm from their combined use highlights the significance of following medical recommendations diligently.

  9. The comprehensive information about Tramadol and Vyvanse usage has shed light on the potential risks involved. Safety precautions are paramount.

    1. Absolutely, understanding the effects, risks, and appropriate usage of these medications is of utmost importance to safeguard one’s well-being.

  10. It’s evident that the combined use of Tramadol and Vyvanse poses serious health risks. Caution and adherence to medical advice are paramount.

    1. Avatar of Chelsea Russell
      Chelsea Russell

      Indeed, the meticulous attention to dosage and time intervals is essential to avoid undesirable effects from these medications.

    2. The information presented about the adverse effects of combining Tramadol and Vyvanse underscores the need for careful and informed usage.

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