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How Long After Advil Can I Take Aleve (And Why)?

Exact Answer: 10 Hours

People falling sick is as natural as getting cured. When a person is born into this world, that person has to experience a lot of things. Centuries back, a simple could become fatal but now due to advancements in medical science, people are getting cured of many serious diseases. It is the old people who need more medication than the young but exceptions exist in all fields.

People can have medicine without any prescription. There is a list of medications, which are kept by each person in their houses. They are mainly for fever, pain, cough and cold, etc. Advil and Aleve are two of the medicines among them. Even though they can be combined during a course, there should be at least a 10-hour gap between them.

How Long After Advil Can I Take Aleve?

NSAIDDuration Of Action
Advil4-8 Hours
Aleve10-12 Hours

Taking Advil, a person should wait for at least 10 hours before having Aleve. This also applies if Aleve is taken first and then Advil. The 10 hours is not a strict schedule, but the gap between the dosage should be at least between 8 to 12 hours. As both of them are pain relievers, it is better to not take them at the same time even if the person is suffering from excruciating pain.

In the market, both Advil and Aleve are not known by their brand name. People recognize them as ibuprofen and naproxen, respectively. Both of them are the name of the drug. both of them are taken only when the person is having a fever or suffering from pain or inflammation. They are both termed NSAID or Non-Steroidal Anti-Inflammatory Drugs. Muscle pain, headaches, menstrual pain, etc., are other circumstances under which the medication is consumed.

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Both of the drugs have a lot of similarities. Even if several medicines are made to cure the same disease, the chemical composition differs most of the time. But in the case of Advil and Aleve, both of their chemical structures are the same and are termed propionic acids. Due to being nonselective NSAIDs, both of them can be combined with COX1 and COX2 enzymes.

Not only similarities, but they also have a few differences. Being the same almost for every aspect, their dosage time and their term of duration of action differ from each other. Their intended use also differs, one is used more than often than the other one.

Why Does It Take Long To Take Advil After Aleve?

Both Advil and Aleve are medicines that are given to people only when they are necessary. The 10-hour gap is not so long when speaking from a medical point of view. When first taken, the medicine needs time for action. Over time, when the effect wears off, another one can be taken. If both of them are taken at the same time it may have a side effect on the person consuming it.

The FDA or popularly known as the Food and Drug Administration, approved the use of both medicines for different purposes, even while both of them have the same chemical composition and are both NSAIDs. If a person is suffering from a rheumatoid disorder, premature infants, fever, etc., Advil is recommended. While if that person is suffering from, rheumatoid arthritis, pain, tendinitis, etc., Aleve will be his or her first choice.

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The duration of action for Advil is much less than Aleve’s. The effects of Advil last for about 4 to 8 hours before another dose is taken. While the effects of Aleve last up to 10 to 12 hours. If necessary, Aleve is taken twice per day. These drugs also have side effects. The side effects include kidney, diseases, cardiovascular diseases, and digestive issues. Moreover, before taking any drugs, the doctor’s advice should be taken.


As mentioned above, there are a few side effects that may occur while the intake of the drugs. If a person has any kind of medical condition regarding kidney, heart, or digestive system, then that person should consult a doctor before taking the drug. Too many NSAIDs can result in many serious conditions. It may cause damage to the kidney and decrease its functionality, and bleeding from the stomach or the intestines.

There are also other problems like the ability to blood clot is delayed, thus increasing the blood loss. IF too much blood is lost, the person may lose his or her life. So every person taking these drugs should be extra careful.


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