How Long Does Advil Take To Work (And Why)?

Exact answer: 30 minutes

Advil is a brand name for ibuprofen, a nonsteroidal anti-inflammatory medicine (NSAID) being used to treat minor aches and pains.

The effectiveness depends on the type of Advil that is taken and how the body reacts to it. Because some Advil medicines are meant to provide speedier recovery, look at the label to learn when really you can take the pills. It’s important to remember that you can only take one dosage of Advil Migraine in a period of 24 hours.

How Long Does Advil Take To Work

How Long Does Advil Take To Work?

For fever reduction or pain relief, Advil tablets should start working in 15-30 minutes and reach maximum effectiveness in one to two hours. Liquid gel capsules, on the other hand, will begin to function slightly faster and peak in approximately an hour.

Advil is a pain reliever that is used to treat a number of conditions. It can be used to relieve pain, decrease inflammation, and bring the body temperature down if a person has a fever.

Adults and kids over the age of 12 can consume two Advil tablets per four to six hours. Unless recommended by a healthcare expert, do not take more than six tablets in 24 hours or take Advil for more than ten days.

Ibuprofen is a pain reliever that can also aid with inflammation and fever. While the time it takes for ibuprofen to start working varies, it normally takes around half an hour to notice symptom relief. Adults should take an OTC ibuprofen dose every 4 to 6 hours.

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Advil is a pain reliever that can be used to treat minor aches and pains caused by:

  1. Cold
  2. Light-headedness
  3. Cramps during menstruation
  4. Toothaches
  5. Muscular pains and backaches
  6. Minor arthritic discomfort
Disease Dosing
Fever OTC: 200-400 mg
Inflammatory Disease 400-800 mg
Osteoarthritis  300 mg
Rheumatoid Arthritis 300 mg

Why Does It Take This Long For Advil To Work?

Advil includes 200 milligrams (mg) of ibuprofen for each adult-strength tablet. Ibuprofen is also available in generic form and is the principal ingredient inside the Motrin brand.

Advil should adequately control fever or slight pain for four to six hours at the prescribed dosage, but it will take roughly a day for the medicine to entirely leave the body. Only a little portion of the Advil dose remains in the bloodstream after six hours.

The speed with which Advil relieves pain is determined by the composition. Its impact lasts for four to eight hours on average, but you must follow the recommendations on the label.

Ibuprofen is quickly metabolized by the body, which means it is chemically converted into another inert substance.

Advil operates by a variety of biochemical methods, including the suppression of cyclooxygenase (COX), an enzyme that aids in the creation of prostaglandins and thromboxane. Prostaglandins help to mediate pain and fevers, thromboxane aids in blood clotting, and COX aids in the maintenance of a protective layer in the lining of the stomach. 

The therapeutic effects of Advil, which include pain relief and fever reduction, are due to the reduced action of prostaglandins. Advil’s gastrointestinal adverse effects are linked to its COX and thromboxane inhibition.

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The effects of ibuprofen take around 30 minutes to become apparent. This timeline, however, might range from one individual to the next and for a variety of reasons.


Advil is only intended for symptomatic relief; it does not treat or cure any ailment or medical condition.

The half-life, or the time it takes for the body to metabolize half of the ibuprofen in the body, is used by healthcare experts to assess ibuprofen metabolism. Ibuprofen has a half-life of roughly two hours in adults. This means that half of the medication is gone in two hours.

Advil might raise your chances of having a heart attack or stroke. With higher dosages or continuous usage of Advil, the danger increases. Another NSAID, aspirin, does not enhance this risk; in fact, it is frequently used to prevent strokes and heart attacks.



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Hi! I'm Nidhi.

Here at the EHL, it's all about delicious, easy recipes for casual entertaining. So come and join me at the beach, relax and enjoy the food.

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