How Long After Nyquil Can I Take Advil (And Why)?

Exact Answer: 4 hours

Everyone wants to be fit and healthy ever and forever besides knowing the fact that this is not possible at all. The human body is so advanced and delicate at the same time. Delicate in the sense of wellness. Many times it happens that we have fallen sick or contracted any virus. There are endless reasons by which we can feel or become unwell. During these happenings, the only thing which we all desire of s our speedy recovery. The medicines which we take during these conditions should possess the least side effects and gives us super-fast results and relief, as per our expectations.

There are endless factors that can irritate or can be painful to no extent, such as fever, cough, cold, menstrual cramps, arthritis, body pain, etc. During any of these happenings, we all want that type of medication that can give us sooner and better relief. NyQuil and Advil are some of them. These are the medicines that are best known for treating various of the above-mentioned happenings. But as we all know, that there must be certain time variations between the intake of two medicines. So, what should be the ideal time gap between the consumption of NyQuil and Advil, or how long after NyQuil can I take Advil and why?

How Long After Nyquil Can I Take Advil

How Long After Nyquil Can I Take Advil?

ObjectiveTotal Time
200mg doseTwo hours
600mg doseSix hours

There are different compositions of each medicine and on the active ingredients, only the effects and side effects of the medicine depend. It is always recommended not to take two different medicines with different compositions simultaneously. As each medicine is manufactured with different compositions to cure different comorbidities and if two medicines with different compositions are taken simultaneously then it could be really dangerous for the human taking it. That’s why it is always recommended not to take medicines with different compositions at the same time.

Nyquil is a medicine which is manufactured by Vicks. It is used to treat minor cough, fever, runny or stuffy nose, sore throat, and headache. The active ingredients of NyQuil are acetaminophen, doxylamine, and dextromethorphan (DXM). All these active ingredients treat a certain symptom. Acetaminophen reduces fever and eliminates minor pain, dextromethorphan lessens the coughing effect, and doxylamine relieves congestion, sneezing, and sore throat as it is an antihistamine. The most common side effects observed with NyQuil are dizziness and drowsiness.

On the other hand, Advil which is also known as ibuprofen is used for reducing pain from different parts of the body such as headache, menstrual cramps, dental pain, arthritis, pain caused due to cough and cold, and muscle ache.

Why Does It Takes That Long After Nyquil Can I Take Advil?

There are different doses in which NyQuil is available, the first is a syrup of 200mg and the second one is 600mg. Both of the syrups contain the same composition but in different amounts.

As mentioned above there should be different time variations between the intakes of NyQuil and Advil, for different doses. If someone is consuming a 200mg syrup of NyQuil, then the individual needs to wait for at least two hours to consume Advil. If a person is or has consumed a 600mg syrup of NyQuil then he/she needs to wait for at least six hours for consuming Advil.

NyQuil contains a drug named acetaminophen, which can relieve all the symptoms for which the medicine is recommended. If you have taken NyQuil then there’s no need, to take ibuprofen on top of the acetaminophen. And if you do so then, you’ll likely gain no additional relief of pain or fever from the ibuprofen, but you’ll be exposed to the possible side effects that ibuprofen can cause (e.g., stomach irritation).

It is recommended to take either NyQuil or Advil at a time. Taking both of them at the same time might burst you into side effects. But acetaminophen and ibuprofen that is NyQuil and Advil can be safely taken together by most adults provided with some hours of time intervals. There is no interaction between ibuprofen and any other meds that you may be taking.


NyQuil and Advil both are different medicines, used to treat different symptoms and both are manufactured using different compositions. If both the medicines will be taken simultaneously then the individual will surely have to face consequences in the form of side effects. It is always advisable not to take any medicine before the doctor’s prescription and there should be always a time variation between the intake of two different composition medicines. Intake of both medicines at the same cannot give you super-fast relief it will lead to side effects that can put you into problems because we all know that unexpected expectations can lead you to problems.


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