How Long To Cook Pork Tenderloin In Oven At 400 (And Why)?

How Long To Cook Pork Tenderloin In Oven At 400 (And Why)?

Exact Answer: 25 Minutes Per Pound Of Meat

Pork tenderloin is a lean cut of meat that cooks quickly. Just remember to thaw the pork before cooking it and cook for an additional 10-15 minutes per pound after the desired temperature has been reached. This will ensure that the pork is cooked through, juicy, and safe to eat. 

One of the favorite things about this dish is how versatile it can be. People like adding fresh herbs, chopped garlic, or maybe even some dried fruit for extra flavor when one prepares in the oven at 400 degrees Fahrenheit. With just one pan, you have deliciously moist pork waiting in just 25 minutes.

How Long To Cook Pork Tenderloin In Oven At 400

How Long To Cook Pork Tenderloin In Oven At 400?

Pork Tenderloin at 40025 minutes
Pork Tenderloin at 37530 to 45 minutes

Pork tenderloin can be cooked in the oven for 25 minutes at 400 degrees Fahrenheit. Cooking it this way leaves the middle slightly undercooked and requires a meat thermometer to make sure it is fully cooked.

The actual cooking time of any meat depends on its thickness and density (i.e. fat content). Average cooking times: 1-1/4 to 2 hours at 275 F or 350 F. A general rule of thumb is about 7 minutes per pound of weight, plus an additional 10 minutes rest before serving for more evenness in temperature distribution and better flavor.

Pork loin roasts require longer than brined roasts such as beef roasts because they are leaner meats with less internal moisture retained in them. Cooking pork tenderloin in the oven at 400 degrees for 25 minutes will be sufficient.

Cook Pork Tenderloin

It is important not to overcook a pork loin in the oven -not only is it unpalatable with a slice of dry, tough meat, but according to USDA-approved cooking guidelines, it can cause major shrinkage that might inadvertently lead one to serve less per person. 

Pork tenderloin cooks more quickly than roasts such as ribs and shoulder, so one should monitor the temperature carefully and take it out of the oven when it has reached 150 degrees F or 160 degrees F. 

This temperature will depend on how thick your meat is, so monitor closely until the desired doneness. Lastly, remember that food tastes better when left unrushed and undisturbed. 

Why To Cook Pork Tenderloin In Oven At 400 For So Long?

According to the National Pork Board, one must cook chops, roasts, loins, and tenderloin should be at a safe internal temperature of 145° F. A three-minute rest is recommended after cooking.

Sear the meat at a high temperature to seal in juices before cooking – Flip occasionally while cooking. Generally, one must turn over the loin after about six minutes of total contact with the heat on one side. It will reach medium-rare between 8 and 12 minutes total.

One can store the pork for later and make leftover recipes. Don’t be hard on yourself if it is not perfect. One can use a thermometer to read the actual temperature. 

Sometimes cooking time may vary depending on the thickness of your cut of meat, so one must make sure to check for doneness with a thermometer before removing from heat. Also, it is better to be mindful of how long one allows the meat to rest after cooking too. 

Cook Pork Tenderloin

Pork tenderloin recipe requirements: oil, salt and pepper, heavy-bottomed roasting pan, and delicious pork.

When cooking, cover it with foil paper to make it extra delicious and retain its juiciness. One can know it is completely cooked if the meat is tender, touch pink, and juicy. The best way to check the doneness of pork is through a probe thermometer and ensure the maximum amount of flavor. The meat is safe to eat when the pork is a little pink.  

One can either leave it as a big piece of meat or cut it in half and make two nice pieces. 


The perfect pork tenderloin recipe is one of the most sought-after secrets in American cuisine. Pork should be cooked at around 400 degrees Fahrenheit for 25 minutes per pound (or 30 minutes if it’s 2 pounds). 

Ensure that the oven is calibrated correctly and preheat it before putting the meat into the pan; this should help maintain an even temperature throughout cooking time. 

One can also cover your roast with aluminum foil after 10 minutes of cooking for additional browning on top without overcooking underneath. Finally, do not forget about basting – use butter or oil as as possible.


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Hi! I'm Nidhi.

Here at the EHL, it's all about delicious, easy recipes for casual entertaining. So come and join me at the beach, relax and enjoy the food.


  1. The article provides valuable insight into why overcooking pork tenderloin can have negative effects. The importance of monitoring the temperature is emphasized well.

  2. Although the cooking time may seem long, the reasons behind it are clearly explained. It makes the whole process more understandable.

    1. I get what you mean. The article relates cooking time to thickness and density, which is quite informative.

  3. This article offers detailed and helpful information on how to cook pork tenderloin in the oven. It’s great to know the best temperature and cooking time for this dish.

    1. I completely agree! What I like most is that it gives precise instructions to ensure the pork is cooked through and safe to eat.

  4. The in-depth explanation of the cooking process, along with the reasoning behind each step, makes this article very informative.

    1. I appreciate that the article doesn’t just give instructions but also educates on the cooking science behind it.

  5. The article’s tips to ensure a juicy and tender pork tenderloin are very helpful. It’s a useful guide for those new to cooking this dish.

    1. Indeed! The clear instructions and detailed explanations are valuable for anyone looking to improve their cooking skills.

  6. The detailed guidelines make it easier to understand the reasons behind suggested cooking times and temperatures.

  7. The cooking time and temperature suggested in this article are perfect for achieving a moist and flavorful pork tenderloin in the oven. Great guidelines!

    1. I appreciate how it provides alternative ideas for enhancing the flavor of the pork tenderloin with fresh herbs and dried fruit. Makes the dish more interesting.

    2. Absolutely! The versatility of the dish is highlighted, and the additional options for adding extra flavor are a nice touch.

  8. The article’s advice on allowing the meat to rest after cooking is a great tip for achieving better flavor. It’s always good to know these extra details.

    1. The article provides a great reminder to be patient with the cooking process. It’s a good addition to the cooking guidelines.

  9. I wish the article delved deeper into the various herbs and dried fruits that could be added for extra flavor. It feels like it’s missing a few details.

  10. The article’s emphasis on the importance of using a thermometer for checking doneness is a valuable part of the guidelines.

    1. I couldn’t agree more. It’s a necessary tool when cooking pork tenderloin to ensure it’s safe to eat.

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