How Long After Nyquil Can You Take Ibuprofen (And Why)?

Exact Answer: After about 3 hours

Nyquil is the medication that is recommended to treat pain, cough and fever. Various brands are available which even differ in their strengths. However, all the medications are available in various countries under various brand names. Acetaminophen is mainly prescribed to elevate pain and fever. Dextromethorphan helps in elevating cough in a patient. Nyquil is mainly used to treat allergies, body pain, common cold and its symptoms and flu.

However, it would be unable to cure the coughing caused by any other reasons other than the common cold. However, just like every medication, this medication should even be used as and when prescribed by the doctor. Improper and excessive usage leads to withdrawal symptoms and side effects.

How Long After Nyquil Can You Take Ibuprofen

How Long After Nyquil Can You Take Ibuprofen?

Minimum time3 hrs
Maximum time5 hrs

Before the intake of the medication, the health condition of the patient should be properly assessed by the doctor. This would help him prescribe the best dosage to the patient which would reduce the risks of side effects caused by excessive intake of the medication. Persons having any kind of liver and kidney disease should avoid such medications. Persons who consume frequent beverages of alcohol should even consult the doctor before taking the medicine.

Nyquil reacts with drugs related to inhibit MAO such as isocarboxazid, selegiline, phenelzine, linezolid, tranylcypromine. Persons who had any such medications related to inhibiting MAO within 15 days should strictly avoid the medication. Persons having health conditions like asthma, stomach infections and ulcers, malfunctioning of the kidney should not consume this medication. The medication may react with their normal medications thereby producing negative results.

Pregnant and breastfeeding mothers should strictly stay away from these medications. These medications may be transferred from the mother’s body to the baby thereby affecting the baby’s health condition. These medications belong to the class of antihistamines which even suppress the production of milk in the baby. Excessive intake of the medication may lead to damage of the liver and kidney thereby leading to death. Hence, it is advised to use this medication as a prescription by the doctor.


Overdose may even lead to further complications. Stomach pain, changes in the color of feces, itching, paleness of body parts reflect the side effects of the intake of an overdose of the medication. Sometimes, skin reactions may even be seen in some extreme cases. Hence, the doctor should be consulted at the appearance of symptoms.

Why Should You Wait So Long To Take Ibuprofen After Nyquil?

Just like Nyquil, ibuprofen is even another kind of medication that is actually an NSAID. It is the most used one because of its anti-inflammatory and analgesic effects. Apart from this, it also has properties to reduce pain and hence is used as OTC. It can inhibit the secretion of prostaglandin and the function of platelets which attribute its properties to the medication. It even has the properties to increase the time of gestation period.

Apart from reducing pain, it is used to stop the growth and spread of polymorphs in the body thereby acting to inhibit the enzymes related to inflammation. This is mainly used in cases of cystic fibrosis. It is even used to induce the retention of sodium in the body. It works antagonistically in response to diuretics. Dental pain and other minor pains are even treated with Ibuprofen. This medication had been used to treat Alzheimer’s Disease and the presence of cancerous cells in the breast.

Ibuprofen has even been in many medical procedures as a pain reliever. It even facilitates clotting by stimulating the production of prostanoids which are mainly related to the process of clotting. It even stimulates the production of thromboxane thereby playing a significant role in the process of clotting. Clotting is very beneficial and essential for the body as it prevents the excessive loss of blood during injuries. It gets assimilated into the body after 2-3 hours of intake and starts showing its effects.


If Ibuprofen is taken after taking some food, then the process of assimilation is slow and is steady. The medication gets slowly released into the blood thereby producing effects. The absorption rate of this medication is slightly higher in cases of adults. The body of a child has organs that are not fully developed. This is why the rate of absorption is relatively slow.


Various people wonder if these medications can be used together. The constitution of both these medications is entirely different. Ibuprofen has the potential to cut down inflammation while Nyquil doesn’t have any such properties. However, no drug interactions have been witnessed between these two medications. Taking both of them altogether would have greater effects on relieving pain.

However, it is better to maintain the advised time gap of 3 hours. This would reduce the chances of interactions between the drugs thereby reducing the chances of side effects too. However, both these medications should be taken after consumption of food lest there may be chances of other problems related to the stomach.


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Hi! I'm Nidhi.

Here at the EHL, it's all about delicious, easy recipes for casual entertaining. So come and join me at the beach, relax and enjoy the food.


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