Exact Answer: 1- 2 hours
Losartan is a medication typically used to treat heart problems and even high blood pressure. Its basic function involves lowering blood pressure to a considerable extent to reduce the chances of stroke or other heart-related issues. It also helps in maintaining kidney function in cases where diabetes patients need them. Losartan is a fairly widely used drug but is deemed unsafe for use during pregnancy. Losartan belongs to a class of drugs that are known as angiotensin II receptor antagonists.
How Long Does It Take For Losartan To Work?
Losartan is metabolized within the liver to an active metabolite (which features a comparable activity to losartan). The time to reach the top or maximum impact after a dosage is 1-2 hours for losartan and 3-4 hours for the metabolite. At its top level, losartan hinders 85% of the impacts of angiotensin II, and 25 to 40% of this restraint endures for 24 hours.
It may take up to a week for noteworthy blood pressure-lowering or kidney impacts to be noted, with maximal impacts happening in 3 to 6 weeks. No bounce-back impact on the withdrawal of losartan has come to light. Losartan can be managed with or without food. Ensure you’re satisfactorily hydrated before beginning this medicine.
The dose of losartan may require alteration depending on how you react to it. It may be managed with other drugs that are too utilized to lower blood pressure (such as diuretics). Losartan may cause a drop in blood pressure, particularly when going from a sitting or lying down position to standing. This may make you’re feeling mixed up and increment your chance of falling over.
Talk to your specialist or a medical practitioner on the off chance that this happens to you. if you observe the development of swelling in your feet, lower legs, or hands, or unexplained weight pick up contact your specialist because it may be a sign that your kidneys not working as well.
Losartan suspension can be refrigerated for even up to 4 weeks. Your specialist may require you to see him or her routinely for checking of your blood pressure, kidney work, or electrolytes.
|Type||Time for which it takes to work/last|
|Metabolite of losartan||3.5 hours|
|Effect of losartan||24 hours|
Why Does It Take That Long For Losartan To Work?
Losartan may be utilized to treat high blood pressure or certain sorts of kidney disease. Losartan works by blocking the impact of angiotensin II, a hormone that causes blood vessels to contract (choke) expanding blood pressure. Blocking angiotensin II broadens (widens) blood vessels which lower blood pressure.
Losartan moreover increments the excretion of certain salts from the kidney. Losartan has a place in a bunch of medications known as angiotensin II receptor blockers (which may be abbreviated to ARBs). Losartan may too be called an angiotensin II receptor antagonist.
Losartan may be utilized to treat high blood pressure in grown-ups and children over the age of six. It may be utilized to diminish the hazard of stroke in individuals with high blood pressure and cleared out ventricular hypertrophy, but this advantage may not apply to African-American people. Lowering blood pressure has been appeared to diminish the hazard of deadly and nonfatal cardiovascular occasions (such as a heart attack or stroke).
This medication May be utilized within the treatment of kidney infection in individuals with type 2 diabetes with a history of high blood pressure and raised research facility markers of creatinine and urinary protein. May to be utilized to improve kidney results within the common populace (barring African-American individuals) without kidney disease. Losartan may be the favored treatment in individuals with more than one sort of heart condition.
Losartan tablets may be made into a suspension for individuals who have trouble swallowing. They are available in three tablet qualities: 25mg, 50mg, and 100mg. Losartan is accessible as non-specific and as the brand name of Cozaar.
Losartan usually takes about 2 hours to come into effect and lasts for around 24 hours. Don’t use losartan in case you’re pregnant. Halt utilizing and tell your specialist right away on the off chance that you ended up pregnant. This medication can cause harm or death to the unborn child if you take the medication during your second or third trimester. Utilize successful birth control.
In greatly uncommon cases, losartan can cause a condition that comes about within the breakdown of skeletal muscle tissue, possibly leading to kidney failure. Call your specialist right away in case you’ve got unexplained muscle torment, delicacy, or shortcoming particularly if you too have a fever, abnormal tiredness, and dim colored urine.