How Long Does Lyrica Stay in Your System (And Why)?

Exact Answer: About 33 hours

Medical science has advanced in leaps and bounds and the results have been both astonishing and beneficial. Today there is a medical-based solution for almost every health problem and very little to question about it. There are medicines for almost every disease and medical condition no matter how complex or how simple.

That is however not simply enough. It is essential to know what goes into the system and how it will affect the body. This is a general responsibility that everyone must follow. Of the many various kinds of drugs available, the ones for nerve damage and similar problems should be paid special attention.

How Long does Lyrica Stay in Your System

How Long Does Lyrica Stay in Your System?

Lyrica is a commonly used popular name for the drug Pregabalin. It is an FDA-approved drug used to treat seizures, nerve damage, and muscle pain in adults. It is an anticonvulsant used to treat nerve damage and pain due to diabetes or shingles. Like most of the prescribed medication for nerve damage, pregabalin does not exactly bind to the GABA neurotransmitters in the brain but it affects the way these neurotransmitters communicate with each other.

There are several other conditions for which this medication can also be prescribed. These include fibromyalgia, seizures, and even a general anxiety disorder.

How long the drug Lyrica stays in a system entirely can be categorized into 3 parts roughly.


The drug pregabalin stays in the system for up to 33 hours affecting the body with its characteristic compounds.


Traces of different drugs are detected in the urine and so how long a drug stays in the system is also more or less depending on how long it stays in the urine. In the case of Lyrica, the traces of the drug can be found in the body for a few days even after it is gone from the system.


The drug Lyrica tends to stay in the hair for a long time, for about up to 90 days approximately. Their traces can be found in the hair and nails very for a long time.

Lyrica Stay in Your System
Part of the BodyTime
Blood33 hours
UrineA few days after 33 hours
HairUp to 90 days

Why Does Lyrica Stay in Your System So Long?

Lyrica is the brand name for the nerve damage prescription drug pregabalin. It is an FDA-approved drug that is used for the treatment of a variety of conditions such as nerve damage and pain because of diabetes or shingles, fibromyalgia, nerve damage from spinal cord injuries, or even simple anxiety disorders or to prevent seizures.

Lyrica belongs to a class of drugs known as antiepileptic drugs which work on the nerves to regulate them and ensure their smooth functioning. The main compound of this drug is pregabalin and this is the compound that reacts with the body. It does not entirely bind itself with the GABA neurotransmitters but it interacts with them in a way that affects their communication and interaction ways with each other.

Lyrica Effect

Thus, Lyrica may take part in various chemical reactions in the body as drugs tend to do. But this only happens for a limited period. Lyrica stays in the blood of the patient for about 33 hours. This means that it will be detected in the blood through tests during this period. The traces of Lyrica may not be found in the blood after approximately 33 hours, but they will be found in the urine for a few more days after that as well.

However, the traces of the drug Lyrica stay in the hair for the longest period. They can be found in the hair for up to 90 days after the drug is gone from the system.


Taking medically prescribed drugs has become a very common part of every adult’s life. It is now just some unavoidable part that comes with the description and with a prescription. However, it is essential to always be aware of what goes into one’s system and how long it stays there as well as how it affects the body while in there.

Lyrica is a drug administered by doctors for mainly nerve damage. It is FDA approved but it is also widely known to have a high chance of being abused. Therefore it is very important to treat it with caution when taking it.



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Hi! I'm Nidhi.

Here at the EHL, it's all about delicious, easy recipes for casual entertaining. So come and join me at the beach, relax and enjoy the food.


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