How Long After Claritin Can I Take Benadryl (And Why)?

How Long After Claritin Can I Take Benadryl (And Why)?

Exact Answer: Twenty Hours

Claritin, which is more popularly known as Loratadine, is also sold by other brand names such as Claratyne and Clarityn. It is one of the medicines present on the list of essential medicines provided by the World Health Organization. This drug is popularly used in the treatment of several allergies in different patients.

The molecular formula of the drug contains twenty-two carbon atoms and two nitrogen atoms, along with four oxygen atoms. The Hydrogen atom is responsible for filling the remaining valences. The molecular mass of the drug is 382.89 grams per mole, and it is administered orally through the mouth.

How Long After Claritin Can I Take Benadryl

How Long After Claritin Can I Take Benadryl?

Claritin is available in many different forms in tablets and syrups. It is also present in the form of oral suspension. The elimination half-life of the drug is close to eight hours. The melting point of Claritin is very high and is approximately 182 degrees celsius or 359 Fahrenheit. The bioavailability of the drug is nearly a hundred percent, and it is one of the most effective medicines in treating medical condition. This medicine is one of the most prescribed medicine for patients with allergies caused due to various infectious pathogens.

Claritin was first synthesized in 1972, and various trials of the medicines were conducted on multiple patients to test the effectiveness of the drug. Finally, the drug was approved for medical use approximately two decades later, in the year 1993. Good results of Claritin are also observed in treating patients suffering from hives and allergic rhinitis. Schering-Plough is credited for synthesizing the medicine in a small pharmaceutical company situated in the United States. This medicine is also sold popularly with another drug named Benadryl.

Time Gap Between Claritin And BenadrylEffect Of The Medicines
Twelve hoursFew side effects but low efficacy
Twenty hoursOne or two side effects with better efficacy

It is advised not to take Claritin and Benadryl together because of the complications involved. If Benadryl is taken after twelve hours of Claritin, then side effects are few, but the efficacy is very low. In contrast, if the time gap is increased to twenty hours, then only one or two side effects are observed, and the effectiveness of the drug also increases many folds.

Why Does It Take That Long After Claritin To Take Benadryl?

Benadryl, also popularly known as Unisom and Sominex, is a popular drug used to treat nausea and symptoms of the common cold. It is also helpful in medical conditions like allergies. The drug can be taken orally through the mouth or injected into the body’s veins. It can also be applied to the skin of the patient. The molecular formula of the drug contains seventeen carbon atoms and one nitrogen atom, along with a solitary oxygen atom. The Hydrogen atom is responsible for filling the remaining valences. The molecular mass of the drug is 255.355 grams per mole.


It takes that long after Claritin to take Benadryl because of the drug composition of both medicines. Both the compounds have similar side effects, and taking them together can increase the chances of getting many adverse folds. If both are consumed together, then the contents of both the drugs mix with each other, and the drugs don’t work very effectively. It is essential to consult a medical expert before taking both drugs.

The two drugs also have several side effects. The most common side effects include anxiety and headaches. Patients might also feel trouble sleeping and nausea after taking this medicine. However, whether the drug can be taken during pregnancy or not is still unclear, but no ill effects have been observed on any mother or child. It is also advised not to drive under the influence of these drugs as it can lead to a loss of concentration and might cause an accident.


Finally, it can be concluded that Claritin is a medicine that is used for patients who are suffering from medical conditions like allergies. The drug was first introduced in 1972; however, it was approved for medical use a few decades later in 1993. It is very effective and is also considered safe by medical experts all around the world.

On average, a patient must keep a time gap of twenty hours between Claritin and Benadryl to prevent getting ill. It has been found that if both these drugs are taken together, then the chances of getting adversely affected increases. It is always crucial to visit a medical practitioner and learn about drug usage to be safe.


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  1. Understanding the history and approval process of Claritin is important for patients who rely on this medication. It instills confidence in its safety and effectiveness.

    1. I completely agree. This comprehensive background information is not commonly found in articles and is highly valuable to readers.

  2. The consideration of the time gap for taking Claritin and Benadryl is essential knowledge for patients. It helps in optimizing the effectiveness of these medications.

    1. Absolutely, this insight is key to ensuring that patients derive the maximum benefit from these medications while minimizing the risks.

  3. The focus on safety while using Claritin and Benadryl is paramount. Patients need accurate information to make well-informed decisions.

    1. Exactly, prioritizing safety and providing clear recommendations for using these medications is crucial for patient well-being.

  4. I’m surprised by the time gap between taking Claritin and Benadryl. It’s fascinating that a 20-hour gap significantly reduces side effects and increases effectiveness.

    1. Indeed, it is intriguing how the time gap between the two drugs influences the efficacy and side effects. The bioavailability plays a crucial role in this contrast.

    2. The details about the time gap provide important practical information for patients and healthcare providers.

  5. The conclusive information about the time gap and effectiveness of Claritin is enlightening. It serves as a practical guideline for patients.

    1. Absolutely, this conclusion offers a valuable recommendation for patients to adhere to the 20-hour gap between Claritin and Benadryl.

    2. The clarity in the conclusion provides patients with clear instructions for the proper usage of these medications, keeping their health and safety in mind.

  6. The detailed explanation of the side effects of Claritin and Benadryl provides a realistic view of what patients may experience, promoting informed decisions.

    1. Agreed, the article accurately presents the potential side effects while clarifying the uncertainty about the impact of these drugs during pregnancy.

  7. The detailed molecular formula information of Claritin and Benadryl is highly informative and provides valuable insight into the drugs’ composition and effects.

    1. I agree, the molecular mass, molecular formula and bioavailability are critical in understanding the efficacy of the drugs.

  8. The comprehensive information about Claritin and Benadryl is presented in an accessible manner, providing patients with vital knowledge for informed decision-making.

    1. The comprehensive nature of the article adds significant value by equipping readers with the necessary knowledge to make informed decisions about these medications.

    2. Absolutely, the clear and concise presentation of detailed medical knowledge facilitates better understanding and empowers patients to make informed choices.

  9. The warning about not taking Claritin and Benadryl together is crucial for patient safety, and consulting a medical expert is essential, as mentioned in the article.

    1. Absolutely, the potential risks associated with combining these medications need to be emphasized, and the recommendation to consult a medical professional is responsible advice.

  10. The detailed information about the effects of combining Claritin and Benadryl is very informative. It raises awareness about potential risks and the importance of following guidelines.

    1. Absolutely, this information is critical to avoid adverse health outcomes. Patients should be well-informed about the risks and follow professional advice.

    2. The clear explanation encourages patients to prioritize their safety and consult medical experts before making decisions about these medications.

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