How Long After Claritin Can I Take Benadryl (And Why)?

Exact Answer: Twenty Hours

Claritin, which is more popularly known as Loratadine, is also sold by other brand names such as Claratyne and Clarityn. It is one of the medicines present on the list of essential medicines provided by the World Health Organization. This drug is popularly used in the treatment of several allergies in different patients.

The molecular formula of the drug contains twenty-two carbon atoms and two nitrogen atoms, along with four oxygen atoms. The Hydrogen atom is responsible for filling the remaining valences. The molecular mass of the drug is 382.89 grams per mole, and it is administered orally through the mouth.

How Long After Claritin Can I Take Benadryl

How Long After Claritin Can I Take Benadryl?

Claritin is available in many different forms in tablets and syrups. It is also present in the form of oral suspension. The elimination half-life of the drug is close to eight hours. The melting point of Claritin is very high and is approximately 182 degrees celsius or 359 Fahrenheit. The bioavailability of the drug is nearly a hundred percent, and it is one of the most effective medicines in treating medical condition. This medicine is one of the most prescribed medicine for patients with allergies caused due to various infectious pathogens.

Claritin was first synthesized in 1972, and various trials of the medicines were conducted on multiple patients to test the effectiveness of the drug. Finally, the drug was approved for medical use approximately two decades later, in the year 1993. Good results of Claritin are also observed in treating patients suffering from hives and allergic rhinitis. Schering-Plough is credited for synthesizing the medicine in a small pharmaceutical company situated in the United States. This medicine is also sold popularly with another drug named Benadryl.

Time Gap Between Claritin And BenadrylEffect Of The Medicines
Twelve hoursFew side effects but low efficacy
Twenty hoursOne or two side effects with better efficacy

It is advised not to take Claritin and Benadryl together because of the complications involved. If Benadryl is taken after twelve hours of Claritin, then side effects are few, but the efficacy is very low. In contrast, if the time gap is increased to twenty hours, then only one or two side effects are observed, and the effectiveness of the drug also increases many folds.

Why Does It Take That Long After Claritin To Take Benadryl?

Benadryl, also popularly known as Unisom and Sominex, is a popular drug used to treat nausea and symptoms of the common cold. It is also helpful in medical conditions like allergies. The drug can be taken orally through the mouth or injected into the body’s veins. It can also be applied to the skin of the patient. The molecular formula of the drug contains seventeen carbon atoms and one nitrogen atom, along with a solitary oxygen atom. The Hydrogen atom is responsible for filling the remaining valences. The molecular mass of the drug is 255.355 grams per mole.

It takes that long after Claritin to take Benadryl because of the drug composition of both medicines. Both the compounds have similar side effects, and taking them together can increase the chances of getting many adverse folds. If both are consumed together, then the contents of both the drugs mix with each other, and the drugs don’t work very effectively. It is essential to consult a medical expert before taking both drugs.

The two drugs also have several side effects. The most common side effects include anxiety and headaches. Patients might also feel trouble sleeping and nausea after taking this medicine. However, whether the drug can be taken during pregnancy or not is still unclear, but no ill effects have been observed on any mother or child. It is also advised not to drive under the influence of these drugs as it can lead to a loss of concentration and might cause an accident.


Finally, it can be concluded that Claritin is a medicine that is used for patients who are suffering from medical conditions like allergies. The drug was first introduced in 1972; however, it was approved for medical use a few decades later in 1993. It is very effective and is also considered safe by medical experts all around the world.

On average, a patient must keep a time gap of twenty hours between Claritin and Benadryl to prevent getting ill. It has been found that if both these drugs are taken together, then the chances of getting adversely affected increases. It is always crucial to visit a medical practitioner and learn about drug usage to be safe.


One request?

I’ve put so much effort writing this blog post to provide value to you. It’ll be very helpful for me, if you consider sharing it on social media or with your friends/family. SHARING IS ♥️