How Long Does It Take For Linzess To Work For Constipation (And Why)?

Exact Answer: Up to 1 week

Linzess is taken for constipation and is an oral constipation medication. People who are struggling with constipation along with irritable bowel syndrome can take the drug Linzess. Linzess would also show effective results for helping chronic constipation, such as idiopathic constipation. The linaclotide or Linzess would take around one week to work for constipation.

The Linzess would work mostly in the intestine. This medication would help in reducing the pain of constipation by increasing bowel movement. Sometimes people may start observing big changes after 12 weeks of taking Linzess.

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How Long Does It Take For Linzess To Work For Constipation?

Linzess Oral MedicationHow Long Does It Take For Linzess To Work For Constipation
Minimum time7 weeks
Maximum time12 weeks

The fluid secretion into the intestinal area can happen by increasing the production of cyclic guanosine monophosphate. This chemical will help in reducing pain sensitivity. Linzess is the brand name of linaclotide medication. The Linzess will not be available as a generic drug. Everyone looking for trying out the effects of Linzess should get it prescribed from the doctor.

A prescription is vital for getting Linzess from the pharmacy. Some people may experience some kind of side effects after using the Linzess. These are:
gas problems
Stomach pain

If someone experiences serious diarrhea issues, then avoid the usage of Linzess. Other side effects such as fatigue, headache, and respiratory infections can also come after using Linzess. Blood passing from the rectum is another side effect of Linzess. Linzess would take around one week to make the stool texture better.

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Linzess also work effectively for helping people with incomplete bowel movement and bloating. Taking the correct dosage of Linzess is vital to avoid any type of side effects. Incorrect dosage can also cause a delay in the working of Linzess.

Everyone should take around 290 mcg daily as this is considered the correct dosage amount for one day. The patient should follow the instructions of the doctor as the dosage may vary for different people. The dosage of chronic idiopathic constipation would be around 145 mcg daily. Never take Linzess after taking the meals.

It’s always correct to take Linzess before having the food at least 30 minutes before the first meal.

Why Does It Take This Long For Lizness To Work For Constipation?

Linzess would take some time to show its effectiveness. Increasing the cyclic guanosine monophosphate would take some time. Taking the medication in time is important to make it work faster and effectively. If someone misses any dosage of the Linzess then this may delay the effectiveness of the Linzess.

If someone skipped the dosage, then the person should avoid taking the dose any other time in the same day. Taking the dosage the next day at the same time would be a better option. Always store the drug properly in a safe place. The storage plays a vital role in the better performance of the medication. As some oral medications may react in extremely hot temperatures.

Keep the drug in its packaging to avoid any contact with moisture. Moisture and excess heat can degrade the quality of the Linzess. The active ingredient in the Linzess would take different times to work inside the body of different people. In some people, the active ingredients linaclotide would work in 5 to 6 days.

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The time of working also depends on the body of the patients. If the constipation issue is extremely severe, then the medication would take more time. If the constipation issue is without any symptoms, then it may get treated in very little time.


Taking Linzess with food is not a wise choice as it would trigger the risk of gastrointestinal intolerance. Therefore taking Linzess without food and before 30 minutes of the meal would be a better choice. Everyone should inform the doctor or expert about any other supplements that they are taking with the Linzess.

People with severe health problems such as heart problems or high diabetes should talk to the doctor before taking Linzess.